How often should I get the O-Shot Treatment? The O-Shot can be a one-time treatment for up to two years of improved sexual wellness. However, studies suggest that a second O-Shot six to twelve months after the first can extend the results achieved.What Are the Adverse Effects of O-shot?Urgent or more frequent urination.Pinching, pressure or pain during injection (Topical numbing agents make this a rare occurrence)Spotting.A feeling of vaginal "fullness"
